4.1+Chromosomes,+genes,+alleles+and+mutations

4 Genetics - 4.1 Chromosomes, genes, alleles and mutations - 4.2 Meiosis - 4.3 Theoretical genetics - 4.4 Genetic engineering and biotechnology - Genetics Labs


 * Assessment statements** (IBO notes added to some point to clearly indicate what needs to be understood and what does not)
 * 4.1.1 || State that eukaryote chromosomes are made of DNA and proteins (no further detail required). ||
 * 4.1.2 || Define gene, allele and genome. ||
 * 4.1.3 || Define gene mutation. ||
 * 4.1.4 || Explain the consequence of a base substitution mutation in relation to the processes of transcription and translation, using the example of sickle-cell anemia. ||

__18 Things you should know about genetics__ Before watching you will be assigned a number(s) - remember and take notes on the information about your number. Later as a class you will be expected to recall your information when your number is called. media type="custom" key="23840172"
 * Starter**

__Mutations__ are a key concept not just in genetics, but are the driving force behind evolution. Watch this video by Paul Andersen of Bozeman Science to understand their relevance. media type="custom" key="23840182"

Log in to the [|DCS Bridge] to obtain your workbooks and supporting resources
 * Workbooks and Worksheets **

An alternative set of notes from [|i-Biology] can be found here media type="custom" key="23840184"

Steven Taylor ([|i-Biology]) has a great presentation to view and take notes from before starting your notebook
 * Presentations and tutorials **

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[|Tour Of The Basics] by the University of Utah is a great way to begin your introduction the genetics topic [|Mutations] are mistakes in our DNA how they occur and what causes them is key not just to genetics, but evolution too.

Sickle cell disease is summarised well in this short video from HHMI.

[|Sickle-cell disease] is an important case study for genetics and mutations this [|video] outlines a breakthrough in the treatment of it. [|Harvard University] has some good information. [|Medline] and the [|National Heart Blood and Lung Institute] have good summaries on the symptoms and causes. Lastly [|Channel4] has a good animations and inheritance charts along with a summary of symptoms.

Use [|click4biology] to review and complete your notes

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 * Activities**
 * 1) In groups discuss and match the key terms and definitions:
 * 1) Review as a class then enter the correct definitions into your workbook in the sections you feel are the most appropriate
 * 2) Complete the workbook
 * 3) Review the workbook in class
 * 4) Complete the 'sickle cell' and for 'harm or benefit' tasks ([|from the bridge]) with book closed then peer mark

> **Gene:** a heritable factor that controls a specific characteristic. (The differences between structural genes, regulator genes and genes coding for tRNA and rRNA are not expected at SL). > **Allele:** one specific form of a gene, differing from other alleles by one or a few bases only and occupying the same gene locus as other alleles of the gene. > **Genome:** the whole of the genetic information of an organism. media type="custom" key="20920810"
 * IB Definitions** (click to show/hide)


 * Useful Links **